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This article is about the second installment in the Call of Duty series. For the console spin-off, see Call of Duty 2: Big Red One
2005 video game
Call of Duty 2 is a 2005 first-person shooter video game developed by Infinity Ward and published by Activision in most regions of the world. It is the second installment of the Call of Duty series. Announced by Activision on April 7, 2005, the game was released for Microsoft Windows on October 25, 2005, and as a launch title for the Xbox 360 on November 22, 2005.[4] Other versions were eventually released for OS X, mobile phones, and Pocket PCs.
The game is set during World War II and the campaign mode is experienced through the perspectives of four soldiers: one in the Red Army, one in the United States Army, and two in the British Army. It contains four individual campaigns, split into three stories, with a total of 27 missions. Many features were added and changed from the original Call of Duty, notably regenerating health and an icon that indicates a nearby grenade about to explode.
The game drew critical praise, particularly for the graphics, sound, and the regenerating health system. The Xbox 360 version sold more than 250,000 copies in its first week, more than 2 million copies by January 2008, and nearly 6 million copies by November 2013.[9] It is considered to be one of the best video games of all time.
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Antibi�ticos: cerca de 700 mil pessoas morrem anualmente v�timas da resist�ncia antimicrobiana � 
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Cientistas anunciaram nesta semana a descoberta de uma nova classe estrutural de antibi�ticos. O artigo com a descobertas foi publicado na revista cient�fica "Nature" e foi apresentado como um avan�o significativo no estudo dessas drogas
profundo (deep learning) para prever atividades de toxicidade, examinando virtualmente mais de 12 milh�es de compostos candidatos.
Esta abordagem inovadora resultou ent�o na identifica��o de uma nova classe de antibi�ticos com potente atividade contra pat�genos resistentes a m�ltiplos medicamentos.Na pesquisa, os cientistas investigaram a atividade antibacteriana dos compostos os testando contra um tipo de bact�ria, o Staphylococcus aureus resistente � meticilina (ou SARM).
Uma inova��o-chave do estudo
foi a capacidade de compreender as informa��es usadas pelo modelo para fazer suas previs�es de pot�ncia antibi�tica. Para isso, os pesquisadores desenvolveram um algoritmo de busca com o intuito de revelar n�o apenas uma estimativa da atividade antimicrobiana de cada mol�cula, mas tamb�m uma previs�o das subestruturas da mol�cula que provavelmente eram respons�veis por essa atividade.
Uso desenfreado de antibi�ticos na pandemia pode levar a 'apag�o' contra bact�rias resistentes
Posteriormente, tr�s modelos de modelos para se prever a a��o antimicrobicida
adicionais de deep learning foram treinados para prever a toxicidade desses compostos para diferentes tipos de c�lulas humanas. Combinando essas informa��es com as previs�es de atividade antimicrobiana, os pesquisadores identificaram compostos capazes de matar microrganismos com efeitos adversos m�nimos no corpo humano.
Dos compostos testados, aproximadamente 280 foram adquiridos e testados contra o MRSA, levando � identifica��o de dois promissores candidatos a antibi�ticos da mesma classe. -"O nosso
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Call of Duty: Advanced Warfare is a 2014 first-person shooter video game published by Activision. The eleventh major installment in the Call of Duty series, the game was developed by Sledgehammer Games for PlayStation 4, Windows and Xbox One, while High Moon Studios developed the versions released on PlayStation 3 and Xbox 360, and Raven Software developed the game's multiplayer and the Exo-Zombies mode.
Advanced Warfare was the first Call of Duty title to be developed primarily by Sledgehammer, following the supporting work the studio did on Call of Duty: Modern Warfare 3 alongside Infinity Ward in 2011. Though the game was released on November 4, 2014, a special edition entitled the Day Zero Edition, which came with bonus in-game content, was released on November 3 for people who pre-ordered the game.
Before the development of Advanced Warfare, Sledgehammer were originally working on a game set during the events of the Vietnam War. Development for Advanced Warfare began in late 2011, shortly before the release of Modern Warfare 3. The game became the first entry in the Call of Duty series since Call of Duty 2 to feature a game engine that has had its majority re-written and built from scratch. For the game's single-player campaign mode, Sledgehammer employed veteran actors Troy Baker and Kevin Spacey in lead roles. The game's story features a futuristic setting, set between 2054 and 2061, and follows Jack Mitchell of the United States Marine Corps and his involvement with Atlas, a private military corporation that sells its services to the highest bidder.
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Aldemir first played poker while at a friend's house on New Year's Eve in 2006. He began by playing freerolls on PokerStars and had his first recorded live cash in January 2012 in a �200 tournament held in Berlin.[2] While playing a tournament in Rozvadov, Czech Republic in 2013, Aldemir allowed another player to use his computer to send money on PokerStars and had his account locked on the site for the next four years. He moved to Vienna soon after to study psychology in university.[3]
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